O-Methyl RNA

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2´ O-Methyl RNA

2ʹ O-Methyl RNA (Oligo-2ʹ O-Methyl nucleotide) is a modified RNA molecule featuring a methyl group on the 2ʹ hydroxyl of its ribose sugar. This structural modification enhances its stability and resistance to enzymatic degradation, making it a valuable tool in various research and therapeutic applications.

Key Features and Benefits

  • Enhanced Stability: Resistant to many ribonucleases and deoxyribonucleases, though not entirely impervious, making it suitable for extended handling and challenging environments.
  • Superior Hybridization: Forms exceptionally stable hybrids with complementary RNA strands, outperforming equivalent DNA or RNA sequences in binding affinity.
  • Versatile Applications: Ideal for antisense studies, siRNA research, and other gene expression-related applications.

Important Information

  • Yield: The expected minimum yield is based on a 20-mer sequence. Actual yield may vary depending on the length and composition of the oligo.
  • Pricing: Catalog prices are subject to change without notice and exclude shipping costs.

Explore the stability and efficiency of 2ʹ O-Methyl RNA with TAG Copenhagen’s expert manufacturing solutions for advanced research and therapeutic development.

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